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Development of plant eliminating formaldehyde
Generally, plants are not able to utilize formaldehyde as a source of carbon. However, bacterium called methylotroph is able to resolve formaldehyde (HCHO) with a single carbon (C1) and utilize it as energy. Extracting 3-hexulose-6-phosphate synthase (HPS) and 6-phospho-3-hexuloisomerase (PHI) from methylotroph and inserting them into a model plant makes it possible to add another pathway in the Calvin cycle of the plant as shown in the picture below and a function to eliminate formaldehyde. Papers on those research results have been published by a research group led by Professor Izui of Kinki University and led by Professor Sakai of Kyoto University in Japan.
HPS：3-hexulose-6-phosphate synthase
PHI：6-phospho-3-hexuloisomerase
References:
・“Visual Biology” Bioscience and Industry Vol.63 No3 (2005) p9-10
・L. M. Chen, H. Yurimoto, K. Z. Li, I. Orita, M.
Akita, N. Kato, Y. Sakai, and K. Izui.
Assimilation of formaldehyde in transgenic plants due to the introduction of the bacterial ribulose monophosphate pathway genes.
Biosci. Biotechnol. Biochem., 2010 Mar 23;74(3):627-35. PMID: 20208346
・Mitsui R, Sakai Y, Yasueda H, Kato N.
A novel operon encoding formaldehyde
fixation: the ribulose monophosphate pathway in the gram-positive
facultative methylotrophic bacterium Mycobacterium gastri MB19.
J Bacteriol.., 182(4) p.944-8., 2000